Primær biliær kolangitt (PBC)
PBC er en autoimmun sykdom av ukjent årsak som særlig rammer kvinner. Tidlig medisinsk behandling bedrer prognosen. Sykdommen ble tidligere kalt primær biliær cirrhose.
Sist oppdatert:
6. mars 2020
Hva er primær biliær kolangitt?
PBC er en autoimmun sykdom hvor immunforsvaret reagerer mot celler i gallegangene i leveren og gir betennelse, arrforandringer og forstyrrelser i leverfunksjonen. Tidlige symptomer er slapphet og plagsom kløe. Andre symptomer som kommer senere i forløpet er fettglinsende avføring, gulsott og blodig oppkast. Symptomer ved langtkommen sykdom er pigmentering og fettknuter i huden.
Sykdommen utvikler seg over tid, og den vil på et tidspunkt ikke la seg helbrede.
Galleblære, galleveier, bukspyttkjertel
PBC er en sjelden sykdom. Det finnes ca. 150-400 med sykdommen per million innbyggere. Forekomsten varierer rundt om i verden, den er høyest i Nord-Europa. Cirka 90 prosent av pasientene er kvinner, hyppigst middelaldrende (40-60 år). Tilstanden er sjelden før 30-års alder.
Tidlig påvisning av sykdommen er viktig fordi effektiv medisinsk behandling kan bremse sykdomsutviklingen og øke overlevelsen uten levertransplantasjon.
Dette dokumentet er basert på det profesjonelle dokumentet Primær biliær kolangitt . Referanselisten for dette dokumentet vises nedenfor
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