Føtalt alkoholsyndrom: Symptomer
Symptomene kan være svært varierende. I spedbarnsalderen kan barnet være dårlig til å ta til seg næring, det er veksthemning, barnet er irritabelt og er forsinket i utviklingen, f.eks. motoriske milepæler, forsinket tale og språkutvikling. De fleste opplever problemer knyttet til hjernen og nervesystemet.
Så godt som alle organer i kroppen kan bli skadet. Mange har et karakteristisk utseende i ansiktet. I tillegg til hjernen er misdannelser i øyne, ører, hjerte, mage-tarmsystem, nyrer, urinveier, muskler og skjelett vanlig.
Eldre barn har hovedsakelig problemer med lærevansker, sen utvikling, tale- og språkproblemer. Fra disse er det en glidende overgang mot de barna som er mentalt tilbakestående med betydelig hjerneskade.
I ungdomsårene er det økt forekomst av rusmisbruk, dårlige skoleprestasjoner, dårlige sosiale ferdigheter og kriminalitet.
Dette dokumentet er basert på det profesjonelle dokumentet Føtalt alkoholsyndrom . Referanselisten for dette dokumentet vises nedenfor
- Vaux KK. Fetal alcohol syndrome. Medscape, last updated Oct 22, 2016. emedicine.medscape.com
- Elliott E. Fetal alcohol spectrum disorders. BMJ Best Practice, last updated April 2018. bestpractice.bmj.com
- American Psychiatric Association. Neurobehavioral disorder associated with prenatal alcohol exposure. In: Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5), American Psychiatric Association, Arlington, VA 2013. p.798.
- Jones KL, Smith DW: Recognition of the fetal alcohol syndrome in early infancy. Lancet 1973; 2: 999-1001 PubMed
- Abel EL, Sokol RJ. Fetal alcohol syndrome is now leading cause of mental retardation. Lancet 1986; 2: 1222. PubMed
- Janisse J, Ager J, Martier S, Sokol, R. Re-estimation of threshold for fetal alcohol syndrome (FAS) using nonlinear regression. Am J Obstet Gynecol 2001; 184: 59. PubMed
- Sande HA, Vold I, Lindemann R et al. Den gravide rusmiddelbruker. Tidsskr Nor Lægeforen 1985; 105: 2315-8. PubMed
- Astley SJ. Profile of the first 1,400 patients receiving diagnostic evaluations for fetal alcohol spectrum disorder at the Washington State Fetal Alcohol Syndrome Diagnostic&Prevention Network. Can J Clin Pharmacol 2010; 17: e132-64. pmid:20335648 PubMed
- Feldman HS, Jones KL, Lindsay S, et al. Prenatal alcohol exposure patterns and alcohol-related birth defects and growth deficiencies: a prospective study. Alcohol Clin Exp Res 2012; 36: 670. pmid:22250768 PubMed
- Lægreid LM, Bruarøy S, Reigstad H. Fosterskade ved alkoholbruk i svangerskap. Tidsskr Nor Lægeforen 2005; 125: 445-7. PubMed
- Alvik A, Aalen OO, Lindemann R. Early fetal binge alcohol exposure predicts high behavioral symptom scores in 5.5-year-old children. Alcohol Clin Exp Res 2013; 37: 1954-62. doi:10.1111/acer.12182 DOI
- Sood B, Delaney-Black V, Covington C, Nordstrom-Klee B, Ager J, Templin T, et al. Prenatal alcohol exposure and childhood behaviour at age 6-7 years: dose response effect. Paediatrics 2001; 108: 34-5. PubMed
- Mukherjee RAS, Hollins S, Abou-Saleh MT, Turk J. Low level alcohol consumption and the fetus. BMJ 2005; 330: 375-6. PubMed
- Cook JL, Green CR, Lilley CM, et al. Fetal alcohol spectrum disorder: a guideline for diagnosis across the lifespan. CMAJ. 2016 Feb 16;188(3):191-7. www.cmaj.ca
- Streissguth AP, Bookstein FL, Barr HM, et al. Risk factors for adverse life outcomes in fetal alcohol syndrome and fetal alcohol effects. J Dev Behav Pediatr 2004; 25: 228-38. pmid:15308923 PubMed
- Elliott EJ, Payne J, Morris A, et al. Fetal alcohol syndrome: a prospective national surveillance study. Arch Dis Child. 2008 Sep;93(9):732-7. PubMed
- Jacobson JL, Jacobson SW. Effects of prenatal alcohol exposure on child development. Alcohol Res Health 2002; 26: 282-6. PubMed
- Strömland K. Visual impairment and ocular abnormalities in children with fetal alcohol syndrome. Addiction Biology 2004; 9: 153-7. PubMed
- Muggli E, Matthews H, Penington A, et al. Association between prenatal alcohol exposure and craniofacial shape of children at 12 months of age. JAMA Pediatr. 2017 Aug 1;171(8):771-80. PubMed
- Valborg L, Lonardson GR, Neff-Smith M et al. Characteristics of children who have full or incomplete fetal alcohol syndrome. J Pediatr 2004; 145: 635-40. PubMed
- Burd L, Cotsonas-Hassel TM, Martsolf JT et al. Recognition and management of fetal alcohol syndrome. Neurotoxicol Teratol 2003; 25: 681-8. PubMed
- Peadon E, Rhys-Jones B, Bower C, et al. Systematic review of interventions for children with fetal alcohol spectrum disorders. BMC Pediatr. 2009 May 25;9:35. DOI: 10.1186/1471-2431-9-35. DOI
- Rangmar J, Hjern A, Vinnerljung B, et al. Psychosocial outcomes of fetal alcohol syndrome in adulthood. Pediatrics 2015; 135: e52-8. doi:10.1542/peds.2014-1915 DOI
- May PA, Gossage JA. Estimating the Prevalence of Fetal Alcohol Syndrome: A Summary. Alcohol Res Health 2001; 25: 159-67.
- May PA, Baete A, Russo J, et al. Prevalence and characteristics of fetal alcohol spectrum disorders. Pediatrics 2014; 134: 855-66. doi:10.1542/peds.2013-3319 DOI