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Magesår forårsaket av NSAIDs

Pasienter som skal bruke NSAIDs, blir advart mot at slik medisin kan forårsake mageplager.

NASIDs
En firedel av sårene i magesekken skyldes skader fra bruk av NSAIDs eller salicylater.

Sist oppdatert:

6. mars 2020

Innhold i artikkelen

Hva er NSAIDs?

NSAIDs er forkortelse for non-steroidal anti-inflammatory drugs og betegnes også antiflogistika. Det er en gruppe medisiner som benyttes til å dempe betennelser i bevegeapparatet - i muskler, sener, ledd. Slike betennelser i bevegeapparatet skyldes ikke bakterier eller virus, men betennelsene forårsakes som regel av en form for overbelastning eller irritasjon i vevet. På fagspråket betegnes det inflammasjon. Det betyr at antibiotika som vi bruker mot bakteriebetennelser (f.eks. penicillin), er uten virkning ved slike belastningslidelser i bevegeapparatet.

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NSAIDs virker ved å dempe betennelsen. Det skjer ved å dempe blodtilførselen til det betente området (blir mindre rødt og varmt), å redusere utsivingen av vevsvæske i det betente vevet (demper hevelsen) og det virker smertestillende. Eksempler på NSAIDs som er i handelen, er Diclofenac, Voltaren, Arthrotec, Brexidol, Piroxicam, Napren, Naproxen, Orudis, Celebra, Celebrex, Arcoxia.

Salicylater har lignende egenskaper som NSAIDs, men virkningen er som regel ikke så sterk. Salicylater er medisiner som Aspirin og fås kjøpt på apoteket i småpakninger uten resept. Mange bruker salisylat fast i lave doser (Albyl-E, 75 mg) som forebyggende medisin mot hjerte- og karsykdom. Albyl-E er overtrukket med et magesaftresistent drasjélag og løses opp først i tarmen.

Vil du vite mer

Dette dokumentet er basert på det profesjonelle dokumentet Magesår . Referanselisten for dette dokumentet vises nedenfor

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