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Acetylsalisylsyre ved hjerte- og karsykdom

Acetylsalisylsyre reduserer risikoen for blodproppdannelse. Det har en klar forebyggende effekt ved etablert sykdom som angina og hjerteinfarkt. Hos friske personer er den forebyggende effekten tvilsom.

Illustrasjonsfoto av en mann som holder opp et brett med tabletter.
Acetylsalisylsyre har i vitenskapelige studier vist seg å ha en beskyttende virkning hos pasienter som har angina pectoris, eller som har gjennomgått hjerteinfarkt og blodpropp (trombose) i hjernen. Illustrasjonsfoto: Colourbox

Sist oppdatert:

6. juli 2020

Acetylsalisylsyre og hjerte-/hjernekarsykdom

Acetylsalisylsyre har vært benyttet som medikament i mer enn 100 år. Eksisterende produkter på markedet er Acetylsalisylsyre og Albyl-E. Tradisjonelt har acetylsalisylsyre vært benyttet som et febernedsettende og smertestillende middel. Det har også evnen til å dempe betennelser og har eksempelvis vært mye brukt i behandlingen av leddgikt. Etterhvert er det også blitt et hyppig brukt preparat i behandlingen av hjertekar sykdommer som et middel som motvirker åreforkalkning (aterosklerose).

Annonse

Acetylsalisylsyre har i vitenskapelige studier vist seg å ha en beskyttende virkning hos pasienter som har angina pectoris, eller som har gjennomgått hjerteinfarkt og blodpropp (trombose) i hjernen. På fagspråket betegnes slik behandling av etablerte sykdommer som sekundærforebygging. Sekundært henspeiler på at dette er behandling som blir gitt etter at man har fått en aterosklerotisk sykdom i hjertet og/eller hjernen, altså en behandling som blir gitt sekundært til at sykdommen har oppstått. Formålet med slik behandling er å forhindre at det skal utvikle seg et nytt hjerteinfarkt eller hjerneslag.

Primærforebygging henspeiler på behandling av friske personer for å hindre utvikling av sykdom. Nytten av primærforebyggende behandling med acetylsalisylsyre av hjerte- og karsykdom har vært omdiskutert.

Dette dokumentet er basert på det profesjonelle dokumentet Angina pectoris, stabil . Referanselisten for dette dokumentet vises nedenfor

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