Trombotisk trombocytopenisk purpura: Symptomer ved TTP
De vanligste symptomene tidlig i sykdommen er uspesifikke og inkluderer magesmerter, kvalme, brekninger og en følelse av svakhet. Siden mange ulike organer kan skades av små blodpropper, gir sykdommen derfor ulike symptomer.
Omtrent halvparten har tegn på skader i sentralnervesystemet enten ved starten av sykdommen eller i forløpet. Symptomene kan være hodepine, forvirring, tap av evne til å snakke, bevissthetsendringer fra lett sløvhet til koma. Typisk er at symptomene kan variere over minutter. Noen har lite uttalte symptomer med kun forbigående forvirring. Ved mer fremskreden sykdom kan det observeres lammelser og kramper.
Andre tegn på sykdommen kan være hudblødninger, svakhet som følge av lav blodprosent, nyresvikt eller svikt i andre organer. Feber er uvanlig. Selv om sykdommen oftest har en akutt start, vil en fjerdedel av pasientene ha hatt symptomer i flere uker før diagnosen stilles.
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Dette dokumentet er basert på det profesjonelle dokumentet Trombotisk trombocytopenisk purpura . Referanselisten for dette dokumentet vises nedenfor
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